Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433775 | 0.99 | KMT2A (0.47) | KMT2AALDH1A1HPGDGAAKCNQ2 | |
| SCHEMBL7432207 | 0.91 | ALDH1A1 (0.56) | KMT2AALDH1A1GAACYP1A2CYP3A4 | |
| SCHEMBL7439374 | 0.85 | KMT2A (0.44) | KMT2AALDH1A1HPGDGAAKCNQ2 | |
| SCHEMBL7432442 | 0.84 | L3MBTL1 (0.44) | KMT2AALDH1A1HPGDGAAMAPT | |
| SCHEMBL7432052 | 0.81 | KDM4E (0.65) | KMT2AALDH1A1HPGDGAACYP1A2 | |
| SCHEMBL7438717 | 0.81 | ALOX15 (0.50) | GAAMAPK1POLB | |
| SCHEMBL7434272 | 0.80 | SELL (0.60) | KMT2AALDH1A1GAAMAPTMEN1 | |
| SCHEMBL7433695 | 0.78 | SELL (0.48) | KMT2AALDH1A1GAACYP1A2CYP3A4 | |
| SCHEMBL7434116 | 0.77 | LTB4R (0.67) | KMT2AHPGDMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10669472 | 0.74 | KCNQ2 (0.62) | KMT2AALDH1A1HPGDGAAKCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |