Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440894 | 0.91 | KMT2A (0.48) | ALDH1A1POLBHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL7433775 | 0.90 | KMT2A (0.47) | ALDH1A1POLBKDM4EKMT2ANPSR1 | |
| SCHEMBL7438717 | 0.78 | ALOX15 (0.50) | POLBGAA | |
| SCHEMBL7434272 | 0.77 | SELL (0.60) | ALDH1A1KMT2AALOX12L3MBTL1LMNA | |
| SCHEMBL7439374 | 0.77 | KMT2A (0.44) | ALDH1A1POLBKMT2AL3MBTL1LMNA | |
| SCHEMBL7432442 | 0.76 | L3MBTL1 (0.44) | ALDH1A1POLBKDM4EKMT2ANPSR1 | |
| SCHEMBL7433695 | 0.75 | SELL (0.48) | ALDH1A1POLBSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL7434116 | 0.75 | LTB4R (0.67) | POLBSMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL7432199 | 0.74 | ALDH1A1 (0.56) | ALDH1A1POLBSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL19084698 | 0.73 | KDM1A (0.67) | ALDH1A1POLBSMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |