Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227362 | 0.83 | POLB (1.00) | POLBALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL14046661 | 0.82 | POLB (0.73) | POLBLMNAALDH1A1MAPTSTAT3 | |
| SCHEMBL7437717 | 0.81 | DGAT1 (0.47) | POLBALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4282303 | 0.81 | POLB (0.71) | POLBLMNAALDH1A1MAPTALOX15 | |
| SCHEMBL7440511 | 0.80 | PKM (0.54) | POLBALDH1A1MAPTHTTUSP2 | |
| SCHEMBL11270973 | 0.80 | POLB (0.51) | POLBLMNAALDH1A1MAPTALOX15 | |
| SCHEMBL11272476 | 0.78 | POLB (0.44) | POLBLMNAALDH1A1MAPTALOX15 | |
| SCHEMBL7435500 | 0.77 | ALDH1A1 (0.57) | POLBLMNAALDH1A1ALOX15USP2 | |
| SCHEMBL7431865 | 0.76 | ATM (0.76) | POLBLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7438084 | 0.75 | NPC1 (0.71) | POLBLMNAALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |