Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443211 | 1.00 | MMP9 (0.47) | MMP9HCRTR1TDP1MEN1KMT2A | |
| SCHEMBL7442580 | 0.89 | UTS2R (0.37) | MMP9PDE2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7442591 | 0.89 | UTS2R (0.37) | MMP9PDE2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7437021 | 0.88 | CTSK (0.44) | MEN1KMT2ACTSK | |
| SCHEMBL7430561 | 0.82 | METAP2 (0.44) | MMP9HCRTR1TDP1MEN1KMT2A | |
| SCHEMBL7430552 | 0.82 | METAP2 (0.44) | MMP9HCRTR1TDP1MEN1KMT2A | |
| SCHEMBL7446905 | 0.81 | TSHR (0.37) | MEN1KMT2APDE2ACTSK | |
| SCHEMBL7446912 | 0.81 | TSHR (0.37) | MEN1KMT2APDE2ACTSK | |
| SCHEMBL7447115 | 0.81 | HDAC1 (0.36) | MEN1KMT2APDE2ACTSK | |
| SCHEMBL7447641 | 0.79 | REN (0.40) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |