Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438986 | 0.90 | SMN1; SMN2 (0.50) | KMT2AMAPTLMNAFAAHSMN1; SMN2 | |
| SCHEMBL7435658 | 0.89 | CNR2 (0.44) | KMT2AMAPTLMNASMN1; SMN2POLB | |
| SCHEMBL7431389 | 0.88 | HPGD (0.51) | KMT2AMAPTLMNASMN1; SMN2POLB | |
| SCHEMBL7428109 | 0.87 | LMNA (0.52) | KMT2AMAPTLMNAFAAHSMN1; SMN2 | |
| SCHEMBL7431708 | 0.87 | FAAH (0.45) | MAPTLMNAFAAHSMN1; SMN2KDM4E | |
| SCHEMBL7434127 | 0.85 | ALOX5 (0.47) | KMT2AMAPTLMNAFAAHSMN1; SMN2 | |
| SCHEMBL7446120 | 0.82 | MAPT (0.44) | KMT2AMAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL7437962 | 0.81 | POLB (0.47) | NAMPTKMT2AMAPTLMNAKDM4E | |
| SCHEMBL7440356 | 0.80 | POLB (0.43) | KMT2AMAPTLMNASMN1; SMN2POLB | |
| SCHEMBL7437912 | 0.80 | KDM4E (0.49) | KMT2AMAPTKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |