Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439165 | 0.89 | ALDH1A1 (0.47) | POLBLMNANPC1ALDH1A1KDM4E | |
| SCHEMBL7440221 | 0.88 | ALDH1A1 (0.47) | LMNANPC1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7431057 | 0.87 | L3MBTL1 (0.42) | LMNANPC1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7438986 | 0.87 | SMN1; SMN2 (0.50) | LMNANPC1ALDH1A1MAPTTP53 | |
| SCHEMBL7431708 | 0.86 | FAAH (0.45) | LMNAALDH1A1KDM4EMAPTCYP2C9 | |
| SCHEMBL7431440 | 0.85 | KDM4E (0.48) | LMNANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL7431439 | 0.85 | KDM4E (0.48) | LMNANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL7428109 | 0.84 | LMNA (0.52) | POLBLMNANPC1MAPTTP53 | |
| SCHEMBL7434127 | 0.83 | ALOX5 (0.47) | POLBLMNANPC1ALDH1A1MAPT | |
| SCHEMBL7439160 | 0.82 | NPC1 (0.42) | LMNANPC1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |