Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431708 | 0.92 | FAAH (0.45) | LMNAFAAHNPSR1TSHRSMN1; SMN2 | |
| SCHEMBL7434127 | 0.91 | ALOX5 (0.47) | LMNARAB9APOLBFAAHNPC1 | |
| SCHEMBL7438986 | 0.90 | SMN1; SMN2 (0.50) | LMNARAB9AFAAHNPC1L3MBTL1 | |
| SCHEMBL7447128 | 0.88 | RAB9A (0.52) | LMNARAB9APOLBNPC1L3MBTL1 | |
| SCHEMBL7435658 | 0.88 | CNR2 (0.44) | LMNARAB9APOLBNPC1KMT2A | |
| SCHEMBL7444281 | 0.87 | NAMPT (0.46) | LMNAPOLBFAAHKMT2ASMN1; SMN2 | |
| SCHEMBL7440356 | 0.87 | POLB (0.43) | LMNARAB9APOLBALOX15NPSR1 | |
| SCHEMBL7438480 | 0.87 | LMNA (0.44) | LMNARAB9ANPC1L3MBTL1NPSR1 | |
| SCHEMBL7431884 | 0.85 | LMNA (0.48) | LMNAPOLBNPC1NPSR1KMT2A | |
| SCHEMBL7437962 | 0.84 | POLB (0.47) | LMNAPOLBNPC1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |