Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967464 | 0.74 | HRH3 (0.65) | SLC6A3HRH3L3MBTL1SIGMAR1L3MBTL3 | |
| SCHEMBL7443798 | 0.73 | PSMB1 (0.50) | HRH3 | |
| SCHEMBL7955357 | 0.72 | HRH3 (0.63) | SLC6A3HRH3L3MBTL1SIGMAR1L3MBTL3 | |
| SCHEMBL13649141 | 0.72 | HRH3 (0.68) | SLC6A3HRH3L3MBTL1SIGMAR1MBTD1 | |
| SCHEMBL10462575 | 0.71 | CA2 (0.44) | TDP1CYP3A4 | |
| SCHEMBL14100544 | 0.71 | HRH3 (0.71) | SLC6A3HRH3L3MBTL1SIGMAR1MBTD1 | |
| SCHEMBL4689587 | 0.71 | HRH3 (0.71) | SLC6A3HRH3L3MBTL1SIGMAR1MBTD1 | |
| SCHEMBL16957341 | 0.70 | PTGS2 (0.42) | SLC6A3CYP3A4 | |
| SCHEMBL20747933 | 0.68 | HRH3 (0.62) | SLC6A3HRH3L3MBTL1SIGMAR1MBTD1 | |
| SCHEMBL2587783 | 0.68 | SLC6A3 (0.64) | SLC6A3HRH3L3MBTL1SIGMAR1MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |