Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | USP9X | Q93008 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10995344 | 0.87 | CHRM2 (0.33) | LMNACHRM2CCR5HTR6ALDH1A1 | |
| SCHEMBL7439952 | 0.86 | CA2 (0.38) | LMNAALDH1A1POLBGAA | |
| SCHEMBL7437169 | 0.86 | LMNA (0.31) | LMNA | |
| SCHEMBL7438346 | 0.85 | — | — | |
| SCHEMBL7429561 | 0.84 | CA2 (0.37) | ALDH1A1 | |
| SCHEMBL7436658 | 0.84 | LMNA (0.39) | LMNAALDH1A1POLBKDM4EGAA | |
| SCHEMBL7434579 | 0.83 | CA2 (0.35) | LMNAALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7444380 | 0.83 | LMNA (0.39) | LMNAALDH1A1POLBKDM4E | |
| SCHEMBL7445252 | 0.83 | ALDH1A1 (0.41) | LMNAALDH1A1 | |
| SCHEMBL7434853 | 0.83 | MTNR1A (0.40) | LMNAALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |