Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 14/20 | 0.41 |
| ▸ | NPY1R | P25929 | 6/20 | 0.39 |
| ▸ | NPY2R | P49146 | 4/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.36 |
| ▸ | CIT | O14578 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7442422 | 0.77 | NPY4R (0.42) | NPY4RNPY1RNPY2RNPY5RKMT2A | |
| SCHEMBL7445644 | 0.77 | NPY4R (0.35) | NPY4RNPY1RNPY2RNPY5RANPEP | |
| Arginine SCHEMBL29664038 | 0.76 | OTC (0.48) | NPY4RKMT2A | |
| Trifluoroacetic Acid SCHEMBL31651399 | 0.76 | NPY4R (0.40) | NPY4RNPY1RNPY2RNPY5R | |
| Arginine SCHEMBL7443448 | 0.76 | OTC (0.48) | NPY4RKMT2A | |
| Arginine SCHEMBL7432633 | 0.76 | OTC (0.48) | NPY4RKMT2A | |
| SCHEMBL7888149 | 0.76 | NOS1 (0.40) | NPY4RNPY1RNPY2RNPY5RANPEP | |
| Hydrochloric Acid SCHEMBL7876078 | 0.75 | NOS1 (0.39) | NPY4RNPY1RNPY2RNPY5RANPEP | |
| SCHEMBL8584832 | 0.74 | NPY1R (0.46) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL9952947 | 0.73 | NOS3 (0.41) | NPY4RNPY1RNPY2RNPY5RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |