Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439560 | 0.75 | LMNA (0.31) | MEN1KMT2A | |
| SCHEMBL7442024 | 0.70 | MAOA (0.44) | MEN1KMT2A | |
| SCHEMBL7442018 | 0.70 | MAOA (0.44) | MEN1KMT2A | |
| SCHEMBL7444026 | 0.67 | MAOA (0.39) | — | |
| SCHEMBL7434413 | 0.67 | MAOA (0.39) | — | |
| SCHEMBL7444576 | 0.65 | LMNA (0.38) | MEN1KMT2A | |
| SCHEMBL7447857 | 0.64 | ALDH1A1 (0.36) | — | |
| SCHEMBL7440895 | 0.64 | ALDH1A1 (0.36) | — | |
| SCHEMBL7523892 | 0.61 | TRPA1 (0.52) | — | |
| SCHEMBL7527686 | 0.61 | TRPA1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641306-A1 | CARBOCYCLIC AND HETEROCYCLIC HIV PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1992021647-A1 | CARBOCYCLIC AND HETEROCYCLIC HIV PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-12-10 | — | — | WO | disclosed |