Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386500 | 0.70 | SLC1A3 (0.35) | LTB4RLTB4R2 | |
| SCHEMBL7293924 | 0.69 | METAP2 (0.35) | — | |
| SCHEMBL7433568 | 0.68 | METAP1 (0.33) | — | |
| SCHEMBL1099742 | 0.67 | ALOX5 (0.33) | — | |
| SCHEMBL7266557 | 0.67 | REN (0.45) | — | |
| SCHEMBL27197672 | 0.67 | ANPEP (0.33) | — | |
| Hydrochloric Acid SCHEMBL7434927 | 0.67 | SLC2A1 (0.33) | — | |
| SCHEMBL9439374 | 0.66 | PER2 (0.41) | — | |
| SCHEMBL643895 | 0.65 | APP (0.36) | — | |
| SCHEMBL3243534 | 0.64 | CYP1A2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826815-A | HYPOTENSIVE | ABBOTT LABORATORIES (US) | 1989-05-02 | — | — | US | disclosed |