Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL467094 | 0.99 | NPC1 (0.54) | NPC1RAB9AACKR3TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7449337 | 0.92 | TMEM97 (0.62) | NPC1RAB9AACKR3TMEM97SIGMAR1 | |
| SCHEMBL11982908 | 0.90 | TMEM97 (0.67) | NPC1RAB9AACKR3TMEM97SIGMAR1 | |
| SCHEMBL3822016 | 0.80 | NPC1 (0.69) | NPC1RAB9AHTR7L3MBTL1TSHR | |
| SCHEMBL4593680 | 0.79 | KMT2A (0.62) | NPC1RAB9AACKR3TMEM97SIGMAR1 | |
| SCHEMBL12123747 | 0.75 | ACHE (0.57) | NPC1RAB9AACKR3TMEM97SIGMAR1 | |
| SCHEMBL13891761 | 0.75 | ACKR3 (0.54) | RAB9AACKR3TMEM97SIGMAR1L3MBTL1 | |
| Sulfuric Acid SCHEMBL7433403 | 0.75 | RAB9A (0.46) | NPC1RAB9ATMEM97SIGMAR1HTR7 | |
| SCHEMBL11982951 | 0.75 | KDM4A (0.60) | NPC1RAB9AACKR3TMEM97SIGMAR1 | |
| SCHEMBL6701558 | 0.74 | L3MBTL1 (0.71) | NPC1RAB9AHTR7L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660819-B1 | NEW N,N,N',N'-TETRASUBSTITUTED-1,2-ETHANEDIAMINE DERIVATIVE COMPOUNDS | FERRER INT (ES) | 1997-10-22 | — | — | EP | claimed |
| US-5561135-A | PSYCHOLOGICAL DISORDERS | FERRER INTERNACIONAL, S.A. (ES) | 1996-10-01 | — | — | US | claimed |
| EP-0660819-A1 | NEW N,N,N',N'-TETRASUBSTITUTED-1,2-ETHANEDIAMINE DERIVATIVE COMPOUNDS. | FERRER INT (ES) | 1995-07-05 | — | — | EP | claimed |
| WO-1995003270-A1 | NEW N,N,N',N'-TETRASUBSTITUTED-1,2-ETHANEDIAMINE DERIVATIVE COMPOUNDS | FERRER INTERNACIONAL, S.A. (ES) | 1995-02-02 | — | — | WO | claimed |