Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.34 |
| ▸ | PPOX | P50336 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450868 | 0.83 | GABRG2 (0.44) | ALDH1A1NPC1HSD17B10GABRA2GABRB2 | |
| SCHEMBL7457553 | 0.83 | GABRA2 (0.46) | NPSR1MAPTMAPK1GABRA2GABRB2 | |
| SCHEMBL7458456 | 0.83 | LMNA (0.45) | NPSR1NPC1MAPTHTTGABRA2 | |
| SCHEMBL7458627 | 0.81 | SLC5A1 (0.41) | ALDH1A1NPSR1TP53MAPTHPGD | |
| SCHEMBL7454183 | 0.79 | GRM5 (0.40) | ALDH1A1NPSR1NPC1MAPTGABRA2 | |
| SCHEMBL7454790 | 0.79 | L3MBTL1 (0.39) | GLP1RL3MBTL1ALDH1A1NPSR1NPC1 | |
| SCHEMBL12065744 | 0.79 | GLP1R (0.35) | GLP1RL3MBTL1ALDH1A1NPSR1NPC1 | |
| SCHEMBL7454502 | 0.78 | NPSR1 (0.48) | L3MBTL1ALDH1A1NPSR1TP53MAPT | |
| SCHEMBL7451577 | 0.75 | GRM5 (0.55) | NPC1MAPTKDM4E | |
| SCHEMBL7452821 | 0.69 | HSD17B3 (0.35) | ALDH1A1NPSR1MAPTGABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151361-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151361-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-12-08 | — | — | WO | disclosed |