Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 12/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2494600 | 0.72 | KIF11 (0.77) | KIF11KCNH2SMN1; SMN2 | |
| SCHEMBL704182 | 0.71 | MAPK1 (0.40) | KIF11KCNH2CYP3A4CYP2C19TAAR1 | |
| SCHEMBL703255 | 0.71 | MAPK1 (0.40) | KIF11KCNH2CYP3A4CYP2C19TAAR1 | |
| SCHEMBL5571950 | 0.69 | KIF11 (0.43) | KIF11CYP3A4CYP2C9CYP2C19TAAR1 | |
| SCHEMBL707299 | 0.69 | KCNN4 (0.35) | KIF11KCNH2CYP3A4CYP2D6TAAR1 | |
| SCHEMBL704100 | 0.69 | KCNN4 (0.35) | KIF11KCNH2CYP3A4CYP2D6TAAR1 | |
| SCHEMBL8703547 | 0.69 | KIF11 (0.71) | KIF11KCNH2MAOA | |
| SCHEMBL2492363 | 0.67 | KIF11 (1.00) | KIF11CYP3A4CYP2C9CYP2C19TAAR1 | |
| SCHEMBL28286751 | 0.67 | KIF11 (0.65) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL707444 | 0.67 | LMNA (0.33) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012134540-A2 | INJECTABLE SYNTHETIC PUR COMPOSITE | VANDERBILT UNIVERSITY (US) | 2012-10-04 | — | — | WO | claimed |