Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 3/20 | 0.43 |
| ▸ | PTPRC | P08575 | 2/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745266 | 1.00 | GRIN2D (0.44) | GRIN2DGRIN2AGRIN2CPTPN1TTR | |
| SCHEMBL860353 | 1.00 | GRIN2D (0.44) | GRIN2DGRIN2AGRIN2CPTPN1TTR | |
| SCHEMBL745518 | 0.99 | GRIN2D (0.43) | GRIN2DGRIN2AGRIN2CPTPN1TTR | |
| SCHEMBL742346 | 0.85 | ALDH1A1 (0.42) | GRIN2DGRIN2AGRIN2CPTPN1TTR | |
| SCHEMBL742864 | 0.84 | ALDH1A1 (0.41) | GRIN2DGRIN2AGRIN2CPTPN1TTR | |
| SCHEMBL3368674 | 0.82 | PTPN1 (0.58) | GRIN2DGRIN2AGRIN2CPTPN1MAPT | |
| SCHEMBL7915823 | 0.81 | PLA2G2D (0.50) | GRIN2DGRIN2AGRIN2CPTPN1TTR | |
| SCHEMBL11243982 | 0.80 | ESR2 (0.44) | MCL1MAPTKDM4EGAAKMT2A | |
| SCHEMBL14120700 | 0.80 | ESR2 (0.44) | MCL1MAPTKDM4EGAAKMT2A | |
| SCHEMBL29774152 | 0.80 | GRIN2D (0.60) | GRIN2DGRIN2AGRIN2CPTPN1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869487-A | Metabolic engineering for microbial production of terpenoid products | 马努斯生物合成股份有限公司 | 2020-03-06 | — | — | CN | claimed |
| EP-4729063-A2 | TREATMENT OF CANCER USING COENZYME Q10 COMBINATION THERAPIES | BPGbio, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20260091003-A1 | METHODS OF TREATMENT OF TEMOZOLOMIDE-RESISTANT GLIOMA USING COENZYME Q10 | BPGBIO INC (US) | 2026-04-02 | — | — | US | disclosed |
| US-20260034073-A1 | COMBINATION THERAPY OF COENZYME Q10 AND RADIATION FOR TREATMENT OF GLIOMA | BPGBIO INC (US) | 2026-02-05 | — | — | US | disclosed |
| EP-2983654-B1 | TREATMENT OF CANCER USING COENZYME Q10 COMBINATION THERAPIES | BPGBIO INC (US) | 2025-11-12 | — | — | EP | disclosed |
| US-12303471-B2 | Methods of treatment of temozolomide-resistant glioma using coenzyme Q10 | BPGBIO, INC. (US) | 2025-05-20 | — | — | US | disclosed |
| US-12209285-B2 | Methods for treatment of oncological disorders using an epimetabolic shifter (coenzyme Q10) | BPGBIO, INC. (US) | 2025-01-28 | — | — | US | disclosed |
| CN-110869487-B | Metabolic engineering for microbial production of terpenoid products | 马努斯生物合成股份有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-110869500-B | Metabolic engineering for microbial production of terpenoid products | 马努斯生物合成股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| US-11452699-B2 | Method of treating or preventing tumors of the central nervous system | BERG LLC (US) | 2022-09-27 | — | — | US | disclosed |
| US-7435571-B2 | Microbial production of COQ10 | DSM IP ASSETS B.V. (NL) | 2008-10-14 | — | — | US | disclosed |
| WO-2008042338-A2 | PRODUCTION OF CAROTENOIDS IN OLEAGINOUS YEAST AND FUNGI | MICROBIA, INC. (US) | 2008-04-10 | — | — | WO | disclosed |
| EP-1866428-A2 | PRODUCTION OF CAROTENOIDS IN OLEAGINOUS YEAST AND FUNGI | Microbia, Inc. (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2007120423-A2 | PRODUCTION OF QUINONE DERIVED COMPOUNDS IN OLEAGINOUS YEAST AND FUNGI | MICROBIA PRECISION ENGINEERING (US) | 2007-10-25 | — | — | WO | disclosed |
| US-20070015237-A1 | Production of carotenoids in oleaginous yeast and fungi | DSM IP ASSETS B.V. (NL) | 2007-01-18 | — | — | US | disclosed |
| WO-2006102342-A2 | PRODUCTION OF CAROTENOIDS IN OLEAGINOUS YEAST AND FUNGI | MICROBIA, INC. (US) | 2006-09-28 | — | — | WO | disclosed |
| US-20060088920-A1 | DNA comprising a nucleotide sequence that encodes decaprenyl diphosphate (DPP) synthase | DSM IP ASSETS B.V. (NL) | 2006-04-27 | — | — | US | disclosed |
| EP-1594967-A1 | MICROBIAL PRODUCTION OF C sb O /sb Q10 | DSM IP Assets B.V. (NL) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004074487-A1 | MICROBIAL PRODUCTION OF COQ10 | DSM IP ASSETS B.V. (NL) | 2004-09-02 | — | — | WO | disclosed |
| WO-2003070926-A1 | NEW NUCLEOTIDE SEQUENCES ENCODING HUMAN PHB: POLYPRENYLTRANSFERASE POLYPEPTIDES | BIOVITRUM AB (SE) | 2003-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12209285-B2 | Methods for treatment of oncological disorders using an epimetabolic shifter (coenzyme Q10) | SLC25A20, NDUFB10, NDUFA10 | GRIN2D 3429/4885GRIN2A 2624/4885GRIN2C 2941/4885 |
| US-20260034073-A1 | COMBINATION THERAPY OF COENZYME Q10 AND RADIATION FOR TREATMENT OF GLIOMA | VEGFA, NDUFA10, NDUFB10 | GRIN2D 1247/4885GRIN2A 1923/4885GRIN2C 3062/4885 |
| US-20260091003-A1 | METHODS OF TREATMENT OF TEMOZOLOMIDE-RESISTANT GLIOMA USING COENZYME Q10 | NDUFA10, NDUFB10, NDUFA5 | GRIN2D 547/4885GRIN2A 1160/4885GRIN2C 1758/4885 |
| US-11452699-B2 | Method of treating or preventing tumors of the central nervous system | NDUFB10, NDUFA10, COQ8A | GRIN2D 1893/4885GRIN2A 645/4885GRIN2C 1146/4885 |
| US-12303471-B2 | Methods of treatment of temozolomide-resistant glioma using coenzyme Q10 | NDUFB10, NDUFA10, NDUFB5 | GRIN2D 1512/4885GRIN2A 716/4885GRIN2C 1249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.