Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454502 | 0.88 | NPSR1 (0.48) | NPSR1BCHEGABRG2GABRB3GABRA5 | |
| SCHEMBL13313 | 0.86 | NPSR1 (0.46) | NPSR1BCHEGABRG2GABRB3GABRA5 | |
| SCHEMBL7445793 | 0.84 | NPSR1 (0.44) | NPSR1BCHEGABRG2GABRB3GABRA5 | |
| SCHEMBL7450722 | 0.84 | NPSR1 (0.44) | NPSR1BCHEGABRG2GABRB3GABRA5 | |
| SCHEMBL7454361 | 0.77 | TP53 (0.52) | NPSR1BCHEGABRG2GABRB3GABRA5 | |
| SCHEMBL7454322 | 0.77 | GABRG2 (0.58) | NPSR1GABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL7457553 | 0.73 | GABRA2 (0.46) | NPSR1GABRG2GABRB3GABRA5MAPT | |
| SCHEMBL7450868 | 0.73 | GABRG2 (0.44) | GABRG2GABRB3GABRA5SMN1; SMN2HSD17B10 | |
| SCHEMBL7458456 | 0.73 | LMNA (0.45) | NPSR1GABRG2GABRB3GABRA5MAPT | |
| SCHEMBL16935867 | 0.71 | ALDH1A1 (0.54) | NPSR1MAPTGAATP53ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151361-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151361-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-12-08 | — | — | WO | disclosed |