Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 7/20 | 0.49 |
| ▸ | MMP1 | P03956 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 7/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5438405 | 0.91 | MMP13 (0.48) | MMP9MMP1LMNAMMP13CXCR3 | |
| SCHEMBL7461641 | 0.90 | KEAP1 (0.46) | MMP9MMP1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6528689 | 0.88 | CXCR3 (0.45) | MMP9MMP1LMNAALDH1A1MMP13 | |
| SCHEMBL5397317 | 0.86 | MMP13 (0.51) | MMP9MMP1LMNAMMP13CXCR3 | |
| SCHEMBL8762678 | 0.86 | MMP1 (0.49) | MMP9MMP1LMNAALDH1A1MMP13 | |
| SCHEMBL7458056 | 0.85 | CXCR3 (0.48) | LMNAALDH1A1MAPTSIGMAR1CXCR3 | |
| SCHEMBL5426083 | 0.82 | CXCR3 (0.45) | MMP9MMP1LMNAALDH1A1MAPT | |
| SCHEMBL2581364 | 0.82 | CXCR3 (0.45) | MMP9MMP1LMNAALDH1A1MAPT | |
| SCHEMBL7620808 | 0.81 | MMP13 (0.41) | MMP9MMP1ALDH1A1MMP13CXCR3 | |
| SCHEMBL4971530 | 0.81 | MMP1 (0.42) | MMP9MMP1ALDH1A1MMP13CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810209-B1 | Alpha - and beta-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | SEARLE & CO (US) | 2002-06-05 | — | — | EP | claimed |
| US-20130317040-A1 | METHODS FOR TREATING SYSTEMIC LUPUS ERYTHEMATOSUS USING HIV PROTEASE INHIBITORS | THE FEINSTEIN INSTITUTE OF MEDICAL RESEARCH (US) | 2013-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130317040-A1 | METHODS FOR TREATING SYSTEMIC LUPUS ERYTHEMATOSUS USING HIV PROTEASE INHIBITORS | SSB, PREP, SERPINB1 | MMP9 153/4885MMP1 79/4885LMNA 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.