Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462498 | 0.90 | PTGS2 (0.58) | TRPM8PTGS2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7457281 | 0.90 | ALDH1A1 (0.52) | TRPM8ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL7462975 | 0.88 | TRPM8 (0.47) | TRPM8PTGS2ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6895646 | 0.78 | PTGS2 (0.58) | TRPM8PTGS2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7457268 | 0.78 | ALDH1A1 (0.52) | TRPM8ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL1249510 | 0.77 | ALDH1A1 (0.52) | TRPM8ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL27428321 | 0.76 | PTGS2 (0.43) | TRPM8PTGS2ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28929348 | 0.72 | RARA (0.54) | TRPM8PTGS2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25397707 | 0.72 | TRPM8 (0.58) | TRPM8ALDH1A1GAASMN1; SMN2TARBP2 | |
| SCHEMBL693401 | 0.71 | ALDH1A1 (0.57) | TRPM8ALDH1A1GAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940401-B1 | 2-CARBONYLTHIAZOLE DERIVATIVES AND USE OF THE SAME | TAISHO PHARMACEUTICAL CO LTD (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-6166033-A | 2-carbonylthiazole derivatives and use of the same | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0940401-A1 | 2-CARBONYLTHIAZOLE DERIVATIVES AND USE OF THE SAME | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1999-09-08 | — | — | EP | disclosed |