Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 19/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452820 | 0.91 | CCR5 (0.34) | CCR5 | |
| SCHEMBL8448824 | 0.88 | NR1D1 (0.34) | CCR5 | |
| SCHEMBL7448989 | 0.88 | SIGMAR1 (0.32) | CCR5 | |
| SCHEMBL7461108 | 0.88 | CCR5 (0.34) | CCR5 | |
| SCHEMBL7461111 | 0.88 | CCR5 (0.34) | CCR5 | |
| SCHEMBL7448950 | 0.85 | CCR5 (0.33) | CCR5 | |
| SCHEMBL8541841 | 0.85 | CCR5 (0.35) | CCR5 | |
| SCHEMBL7451770 | 0.85 | PKM (0.31) | CCR5 | |
| SCHEMBL7561889 | 0.85 | PKM (0.31) | CCR5 | |
| SCHEMBL8536719 | 0.85 | CCR5 (0.40) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882728-B1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO CO (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |