SCHEMBL746168

SCHEMBL746168

CC(C)(C)OC(=O)N[C@H]1CC[C@H](O)CC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BTK Q06187 1/20 0.54
EPHX2 P34913 2/20 0.52
CTSK P43235 2/20 0.50
KDM1A O60341 1/20 0.50
MAOB P27338 1/20 0.50
GAA P10253 2/20 0.49
EPHX1 P07099 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
DRD2 P14416 2/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
MERTK Q12866 1/20 0.42
JAK1 P23458 2/20 0.42
JAK2 O60674 1/20 0.42
TYK2 P29597 1/20 0.42
JAK3 P52333 1/20 0.42
CYP2C9 P11712 1/20 0.42
HSD11B1 P28845 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1204562 1.00 BTK (0.54) BTKEPHX2CTSKKDM1AMAOB
SCHEMBL746169 1.00 BTK (0.54) BTKEPHX2CTSKKDM1AMAOB
SCHEMBL6260146 0.93 BTK (0.60) BTKEPHX2CTSKKDM1AMAOB
SCHEMBL6259821 0.93 BTK (0.60) BTKEPHX2CTSKKDM1AMAOB
SCHEMBL6260151 0.93 BTK (0.60) BTKEPHX2CTSKKDM1AMAOB
SCHEMBL3702157 0.92 BTK (0.61) BTKEPHX2CTSKKDM1AMAOB
SCHEMBL3702152 0.92 BTK (0.61) BTKEPHX2CTSKKDM1AMAOB
SCHEMBL1406894 0.92 BTK (0.61) BTKEPHX2CTSKKDM1AMAOB
SCHEMBL10343938 0.92 BTK (0.61) BTKEPHX2CTSKKDM1AMAOB
Methyl Alcohol SCHEMBL28082230 0.90 BTK (0.59) BTKEPHX2CTSKKDM1AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 544 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260053932-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR AND ASSOCIATED METHODS OF USE ARVINAS OPERATIONS INC (US) 2026-02-26 US disclosed
EP-4688742-A1 CYCLOHEXYL OR HETEROCYCLOALKYL BETA-HYDROXY ALKYL AMINES FOR USE IN THE TREATMENT OF HYPERGLYCAEMIA AND DISORDERS CHARACTERISED BY HYPERGLYCAEMIA Atrogi AB (SE) 2026-02-11 EP disclosed
US-20260035384-A1 COMPOUND CONTAINING CYCLOHEXYL CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) 2026-02-05 US disclosed
EP-4685141-A1 ISOINDOLINE DERIVATIVE, BENZOINDOLE DERIVATIVE AND USE THEREOF Shanghai Helioson Pharmaceutical Co., Ltd. (CN) 2026-01-28 EP disclosed
EP-4648763-A2 COMPOUNDS FOR FGFRS INHIBITORS Cogent Biosciences, Inc. (US) 2025-11-19 EP disclosed
US-12419960-B2 Compounds and methods for the targeted degradation of androgen receptor and associated methods of use ARVINAS OPERATIONS, INC. (US) 2025-09-23 US disclosed
US-20250241918-A1 NOVEL USE OF PYRAZOLOPYRIMIDINE COMPOUND Hefei Youyuan Pharmaceutical Co., Ltd. (CN) 2025-07-31 US disclosed
US-20250235543-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2025-07-24 US disclosed
US-20250195518-A1 INDAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2025-06-19 US disclosed
WO-2025108406-A1 HETEROCYCLIC COMPOUND OF BIFUNCTIONAL CHIMERA FOR TARGETED DEGRADATION OF ANDROGEN RECEPTOR, AND USE THEREOF 广东东阳光药业股份有限公司 2025-05-30 WO disclosed
US-5726172-A BENZOXAZINONE DERIVATIVES; TREATMENT OF PRETERM LABOR, DYSMENORRHEA MERCK & CO., INC. (US) 1998-03-10 US disclosed
US-5691323-A BENZIMIDAZOL-2-ONES MERCK & CO., INC. (US) 1997-11-25 US disclosed
EP-0644872-B1 ORNITHINE DECARBOXYLASE INHIBITING CYCLIC AMINOOXY COMPOUNDS CIBA GEIGY AG (CH) 1997-03-19 EP disclosed
US-5574044-A BENZIMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF MYOPIA MERCK & CO., INC. (US) 1996-11-12 US disclosed
US-5516806-A ANTITUMOR CIBA-GEIGY CORPORATION (US) 1996-05-14 US disclosed
WO-1996013262-A1 MUSCARINE ANTAGONISTS MERCK & CO., INC. (US) 1996-05-09 WO disclosed
WO-1996002553-A2 AMINO PURINE-β-D-RIBOFURANURONAMIDE DERIVATIVES GLAXO GROUP LIMITED (GB) 1996-02-01 WO disclosed
EP-0644872-A1 ORNITHINE DECARBOXYLASE INHIBITING CYCLIC AMINOOXY COMPOUNDS. CIBA GEIGY AG (CH) 1995-03-29 EP disclosed
WO-1994024093-A1 ORNITHINE DECARBOXYLASE INHIBITING CYCLIC AMINOOXY COMPOUNDS CIBA-GEIGY AG (CH) 1994-10-27 WO disclosed
US-5166403-A Liquid crystals SHOWA DENKO K.K. (JP) 1992-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250195518-A1 INDAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF HPGDS, PTGIS, HPGD BTK 2879/4885EPHX2 1734/4885CTSK 1068/4885
US-12419960-B2 Compounds and methods for the targeted degradation of androgen receptor and associated methods of use AR, ADRM1, CRBN BTK 4430/4885EPHX2 2531/4885CTSK 2470/4885
US-20250241918-A1 NOVEL USE OF PYRAZOLOPYRIMIDINE COMPOUND NLRP3, NLRP1, CASP1 BTK 2347/4885EPHX2 586/4885CTSK 1270/4885
US-20260035384-A1 COMPOUND CONTAINING CYCLOHEXYL CYP11B1, CYP4A11, CYP11B2 BTK 1747/4885EPHX2 903/4885CTSK 3060/4885
US-20250235543-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS DDB1, DCLRE1A, TP53BP1 BTK 3955/4885EPHX2 4051/4885CTSK 2636/4885
US-20260053932-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR AND ASSOCIATED METHODS OF USE ADRM1, AR, CRBN BTK 2864/4885EPHX2 3632/4885CTSK 3790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.