Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474484 | 0.89 | ALDH1A1 (0.44) | SMN1; SMN2MAPTRAB9AKDM4EGAA | |
| SCHEMBL7462635 | 0.87 | RORC (0.38) | TDP1MAPTRAB9AKDM4EGAA | |
| SCHEMBL7053331 | 0.82 | HCAR3 (0.40) | SMN1; SMN2MAPTRAB9ALMNAKDM4E | |
| SCHEMBL6497602 | 0.81 | MEN1 (0.49) | TDP1SMN1; SMN2MAPTKMORAB9A | |
| SCHEMBL7467119 | 0.81 | GAA (0.40) | SMN1; SMN2KDM4EGAAHSD17B10HCAR3 | |
| SCHEMBL7463190 | 0.80 | GCK (0.40) | SMN1; SMN2MAPTEPHX2RAB9ALMNA | |
| SCHEMBL382765 | 0.80 | EPHX2 (0.48) | NPY2REPHX2CNR2KDM4EGAA | |
| SCHEMBL7468836 | 0.78 | EPHX2 (0.41) | SMN1; SMN2MAPTEPHX2KMOIRAK4 | |
| SCHEMBL7469575 | 0.78 | ITGB3 (0.61) | — | |
| SCHEMBL382582 | 0.78 | USP2 (0.40) | SMN1; SMN2KDM4EGAAHCAR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |