Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978800 | 0.73 | ADRA1A (0.43) | OPRD1OPRK1ALDH1A1LMNAGAA | |
| SCHEMBL6970257 | 0.73 | OPRD1 (0.41) | OPRD1OPRM1OPRK1ALDH1A1LMNA | |
| SCHEMBL7464135 | 0.72 | ADRA1A (0.44) | ALDH1A1LMNAHTTL3MBTL1MEN1 | |
| SCHEMBL6976571 | 0.72 | ADRA1A (0.40) | OPRD1OPRM1OPRK1ALDH1A1LMNA | |
| SCHEMBL6975114 | 0.71 | OPRD1 (0.44) | OPRD1OPRM1OPRK1ALDH1A1LMNA | |
| SCHEMBL6975631 | 0.70 | OPRD1 (0.38) | OPRD1OPRM1OPRK1ALDH1A1LMNA | |
| SCHEMBL6971806 | 0.69 | OPRD1 (0.42) | OPRD1OPRM1OPRK1ALDH1A1LMNA | |
| SCHEMBL6975764 | 0.68 | CYP11B2 (0.41) | OPRD1OPRM1OPRK1ALDH1A1HRH3 | |
| SCHEMBL6972934 | 0.68 | PKM (0.45) | OPRD1OPRM1OPRK1GAA | |
| SCHEMBL6979774 | 0.67 | OPRD1 (0.41) | OPRD1OPRM1OPRK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202984-A1 | NOVEL DIPHENYL-PIPERIDINE DERIVATE | AstraZeneca UK Limited (GB) | 2002-05-08 | — | — | EP | claimed |
| WO-2001005782-A1 | NOVEL DIPHENYL-PIPERIDINE DERIVATE | ASTRAZENECA UK LIMITED (GB) | 2001-01-25 | — | — | WO | claimed |