Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21176819 | 0.78 | GRM4 (0.51) | KDM4EALDH1A1MAPTADORA2AADORA1 | |
| SCHEMBL7470843 | 0.76 | ALDH1A1 (0.38) | KDM4EALDH1A1GAAMAPTPKM | |
| SCHEMBL9846327 | 0.76 | KDM4E (0.60) | KDM4EALDH1A1GAAMAPTPKM | |
| SCHEMBL7471769 | 0.73 | ALDH1A1 (0.44) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL7462995 | 0.70 | KDM4E (0.57) | KDM4EALDH1A1PKMHPGDALOX15 | |
| SCHEMBL7467894 | 0.70 | ABL1 (0.48) | MAPTLMNAADORA2ARAB9AMEN1 | |
| SCHEMBL13849699 | 0.69 | TDP1 (0.43) | KDM4EALDH1A1GAAMAPTPKM | |
| SCHEMBL17253104 | 0.69 | PDPK1 (0.39) | KDM4EALDH1A1MAPTPKMHPGD | |
| SCHEMBL3366391 | 0.68 | ASIC3 (0.46) | KDM4EALDH1A1GAAMAPTPKM | |
| SCHEMBL22232393 | 0.67 | ADRB2 (0.41) | KDM4EALDH1A1MAPTHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233461-B2 | 4,5,6-Substituted-2-pyrimidinamines | AMERICAN CYANAMID CO (US) | 2002-05-29 | — | — | EP | disclosed |