Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | DKK1 | O94907 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476570 | 0.78 | KDM4E (0.64) | ALDH1A1MAPTNPC1HSD17B10KDM4E | |
| SCHEMBL2197762 | 0.74 | ALDH1A1 (0.35) | ALDH1A1MAPTNPC1KDM4EROCK1 | |
| SCHEMBL7464636 | 0.73 | KDM4E (0.38) | ALDH1A1MAPTHSD17B10KDM4EMEN1 | |
| SCHEMBL7467894 | 0.72 | ABL1 (0.48) | MAPTNPC1MEN1KMT2ACYP1A2 | |
| SCHEMBL7462995 | 0.72 | KDM4E (0.57) | ALDH1A1NPC1HSD17B10KDM4EMEN1 | |
| SCHEMBL4313732 | 0.72 | ALDH1A1 (0.55) | ALDH1A1MAPTNPC1HSD17B10GFER | |
| SCHEMBL12133833 | 0.71 | MAPT (0.52) | ALDH1A1MAPTNPC1HSD17B10GFER | |
| SCHEMBL5712470 | 0.70 | ALDH1A1 (0.41) | ALDH1A1MAPTNPC1HSD17B10GFER | |
| SCHEMBL11996764 | 0.69 | HDAC1 (0.48) | ALDH1A1MAPTNPC1HSD17B10GFER | |
| SCHEMBL2980443 | 0.69 | DKK1 (0.43) | ALDH1A1MAPTNPC1HSD17B10GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233461-B2 | 4,5,6-Substituted-2-pyrimidinamines | AMERICAN CYANAMID CO (US) | 2002-05-29 | — | — | EP | disclosed |