Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | CLK1 | P49759 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463810 | 0.84 | SMN1; SMN2 (0.45) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL7465177 | 0.83 | S1PR2 (0.49) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL7468043 | 0.81 | MAPT (0.48) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL7472833 | 0.81 | MAPT (0.48) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL7468103 | 0.81 | GAA (0.44) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL7563746 | 0.80 | MAPT (0.49) | ALDH1A1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL7465244 | 0.80 | F10 (0.43) | MEN1KMT2AMAPTS1PR2THRB | |
| SCHEMBL7460699 | 0.79 | NLRP3 (0.45) | ALDH1A1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL7464635 | 0.78 | CMA1 (0.37) | MEN1KMT2ALMNAMAPTS1PR2 | |
| SCHEMBL7468006 | 0.78 | MAPT (0.46) | ALDH1A1MEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |