Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472833 | 0.88 | MAPT (0.48) | ALDH1A1MAPTHTTPOLBLMNA | |
| SCHEMBL7461911 | 0.85 | MAPT (0.44) | ALDH1A1MAPTPOLBLMNASMN1; SMN2 | |
| SCHEMBL7468006 | 0.84 | MAPT (0.46) | ALDH1A1MAPTHTTPOLBLMNA | |
| SCHEMBL7563746 | 0.83 | MAPT (0.49) | ALDH1A1MAPTPOLBLMNAKMT2A | |
| SCHEMBL7468103 | 0.82 | GAA (0.44) | ALDH1A1MAPTHTTNPC1RAB9A | |
| Iodide SCHEMBL7468583 | 0.79 | MAPT (0.43) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL7472667 | 0.78 | TP53 (0.42) | MAPTPOLBSMN1; SMN2TP53 | |
| SCHEMBL7460699 | 0.78 | NLRP3 (0.45) | ALDH1A1MAPTPOLBLMNASMN1; SMN2 | |
| SCHEMBL7467037 | 0.78 | SLC1A3 (0.43) | KMT2AMEN1CA1CA2CA9 | |
| SCHEMBL7465884 | 0.77 | AKR1C3 (0.38) | ALDH1A1MAPTHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |