Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470189 | 0.91 | GRIN2B (0.36) | RAB9AGRIN2BKAT6AKDM4EHTT | |
| SCHEMBL6500739 | 0.86 | RAB9A (0.34) | RAB9AGRIN2BKMT2AKDM4EHTT | |
| SCHEMBL7468819 | 0.85 | KAT6A (0.43) | GRIN2BKAT6AALDH1A1L3MBTL1 | |
| SCHEMBL6498897 | 0.83 | ITGB3 (0.47) | — | |
| SCHEMBL6501436 | 0.79 | GRIN2B (0.41) | GRIN2BKMT2AKDM4EALDH1A1 | |
| SCHEMBL7457979 | 0.79 | SFRP1 (0.42) | KAT6AKDM4EHTTDRD4ALDH1A1 | |
| SCHEMBL7469405 | 0.79 | KMT2A (0.37) | RAB9AKAT6AKMT2AKDM4EHTT | |
| SCHEMBL6498054 | 0.77 | RAB9A (0.34) | RAB9AGRIN2BKMT2AKDM4EHTT | |
| SCHEMBL7464729 | 0.77 | CCR2 (0.38) | RAB9AGRIN2BKMT2AKDM4EHTT | |
| SCHEMBL7463691 | 0.77 | KDM4E (0.52) | RAB9AKAT6AKDM4EHTTDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | claimed |
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | disclosed |