SCHEMBL746722

SCHEMBL746722

COc1ccc2c(c1)OCO2

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
MAPK1 P28482 1/20 0.56
KMT2A Q03164 7/20 0.55
MEN1 O00255 4/20 0.55
MAPT P10636 4/20 0.55
NPC1 O15118 5/20 0.54
RAB9A P51151 5/20 0.54
SMN1; SMN2 Q16637 4/20 0.54
HPGD P15428 2/20 0.54
KDM4E B2RXH2 1/20 0.54
PKM P14618 1/20 0.54
MAOB P27338 1/20 0.53
CTNNB1 P35222 1/20 0.53
WNT3A P56704 1/20 0.53
LMNA P02545 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL745193 0.87 PKM (0.54) ALDH1A1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL30627606 0.87 PKM (0.54) ALDH1A1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL6482119 0.84 ALDH1A1 (0.64) ALDH1A1KMT2AMEN1MAPTNPC1
SCHEMBL16230592 0.83 KMT2A (0.43) ALDH1A1MAPK1KMT2AMEN1MAPT
SCHEMBL31371765 0.83 RAB9A (0.48) MAPTNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL6165864 0.82 ALDH1A1 (0.78) ALDH1A1MAPK1KMT2AMEN1NPC1
SCHEMBL16773395 0.82 MAPT (0.53) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL107850 0.82 MAPT (0.53) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL14959930 0.82 MAPT (0.53) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL15982627 0.82 MAPT (0.53) KMT2AMEN1MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-20170044418-A1 HIGH TEMPERATURE STABILIZER FOR POLYMER-BASED TREATMENT FLUIDS SCHLUMBERGER TECHNOLOGY CORP (US) 2017-02-16 US claimed
WO-2016160363-A1 METHOD FOR TREATING A SUBTERRANEAN FORMATION SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2016-10-06 WO claimed
US-20160289544-A1 METHOD FOR TREATING A SUBTERRANEAN FORMATION SCHLUMBERGER TECHNOLOGY CORPORATION 2016-10-06 US claimed
WO-2015171857-A1 HIGH TEMPERATURE STABILIZER FOR POLYMER-BASED TREATMENT FLUIDS SCHLUMBERGER CANADA LIMITED (CA) 2015-11-12 WO claimed
CN-101258119-B Process for preparing 3, 4-dioxo-substituted aromatic aldehydes ENDURA SPA 2014-06-18 CN claimed
CN-101258119-A Process for preparing 3, 4-dioxo-substituted aromatic aldehydes ENDURA SPA (IT) 2008-09-03 CN claimed
EP-4680226-A2 ACYLSULFONAMIDE KAT6A INHIBITORS Olema Pharmaceuticals, Inc. (US) 2026-01-21 EP disclosed
US-20260015327-A1 ACYLSULFONAMIDE KAT6A INHIBITORS OLEMA PHARMACEUTICALS INC (US) 2026-01-15 US disclosed
US-12428379-B2 Acylsulfonamide KAT6A inhibitors OLEMA PHARMACEUTICALS, INC. (US) 2025-09-30 US disclosed
US-20250250294-A1 COMPOUND, METAL COMPLEX, OLEFIN POLYMERIZATION CATALYST COMPOSITION, OLEFIN POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING OLEFIN-BASED POLYMER MITSUBISHI CHEMICAL CORPORATION (JP) 2025-08-07 US disclosed
EP-4596562-A1 COMPOUND, METAL COMPLEX, CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PRODUCING OLEFIN POLYMER Mitsubishi Chemical Corporation (JP) 2025-08-06 EP disclosed
CN-119998304-A Compound, metal complex, catalyst composition for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer 三菱化学株式会社 2025-05-13 CN disclosed
EP-0778833-A1 ENDOTHELIN RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1997-06-18 EP disclosed
WO-1997004781-A1 ENDOTHELIN RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1997-02-13 WO disclosed
WO-1996030358-A1 PHENYL DERIVATIVES USEFUL AS ENDOTHELIN RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1996-10-03 WO disclosed
WO-1996007653-A1 ENDOTHELIN RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1996-03-14 WO disclosed
US-4865617-A Dyeing compositions for keratinous fibres, especially for human hair, containing oxidation dye precursors and heterocyclic couplers L'OREAL (FR) 1989-09-12 US disclosed
US-4058607-A DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES AIRWICK INDUSTRIES, INC. (US) 1977-11-15 US disclosed
US-3962415-A Insecticide evaporator comprising DDVP with synergized benzodioxole compound as stabilizer AIRWICK INDUSTRIES, INC. (US) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12428379-B2 Acylsulfonamide KAT6A inhibitors KAT6A, KAT2A, KAT6B ALDH1A1 2242/4885MAPK1 2706/4885KMT2A 67/4885
US-20250250294-A1 COMPOUND, METAL COMPLEX, OLEFIN POLYMERIZATION CATALYST COMPOSITION, OLEFIN POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING OLEFIN-BASED POLYMER OSTC, PORCN, POF1B ALDH1A1 2226/4885MAPK1 1564/4885KMT2A 1852/4885
US-20260015327-A1 ACYLSULFONAMIDE KAT6A INHIBITORS KAT6A, KAT2A, KAT6B ALDH1A1 1068/4885MAPK1 1838/4885KMT2A 104/4885
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR ALDH1A1 4757/4885MAPK1 3024/4885KMT2A 3227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.