Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468270 | 0.97 | MAPT (0.40) | MAPTGAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7464180 | 0.87 | ACHE (0.40) | MAPTLMNAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7468284 | 0.83 | MAPT (0.43) | MAPTGAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7469778 | 0.80 | MAPT (0.45) | MAPTGAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7475788 | 0.79 | MAPT (0.40) | MAPTGAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7470183 | 0.78 | MAPT (0.42) | MAPTGAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7475565 | 0.77 | ALDH1A1 (0.53) | MAPTGAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7467291 | 0.77 | EGFR (0.44) | MAPTLMNAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7469735 | 0.76 | LMNA (0.47) | MAPTGAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7459038 | 0.75 | MAPT (0.43) | MAPTGAALMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |