Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.34 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.33 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 7/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ESRRG | P62508 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL749993 | 0.92 | LPAR1 (0.39) | SRCSLC13A5HDAC1HDAC6LPAR1 | |
| SCHEMBL745530 | 0.90 | HDAC1 (0.41) | SRCSLC13A5HDAC1HDAC6LPAR1 | |
| SCHEMBL750906 | 0.89 | TP53 (0.39) | SRCSLC13A5HDAC1HDAC6LPAR1 | |
| SCHEMBL747722 | 0.89 | ESRRG (0.41) | SRCSLC13A5HDAC1HDAC6HIF1A | |
| SCHEMBL751065 | 0.88 | SRC (0.38) | SRCSLC13A5HDAC1HDAC6HIF1A | |
| SCHEMBL749104 | 0.87 | SLC13A5 (0.35) | SLC13A5TAOK1TAOK3LPAR1LPAR5 | |
| SCHEMBL750133 | 0.86 | SRC (0.36) | SRCSLC13A5HDAC1HDAC6LPAR1 | |
| SCHEMBL747958 | 0.85 | TP53 (0.38) | SRCSLC13A5LPAR1LPAR5PTGER2 | |
| SCHEMBL750950 | 0.85 | SRC (0.36) | SRCSLC13A5HDAC1HDAC6HIF1A | |
| SCHEMBL748197 | 0.85 | SRC (0.36) | SRCSLC13A5HDAC1HDAC6LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |