Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.35 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 2/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750950 | 0.90 | SRC (0.36) | SRCSLC13A5HIF1AHDAC1NR1H4 | |
| Hydrochloric Acid SCHEMBL751875 | 0.89 | SRC (0.36) | SRCSLC13A5HIF1AHDAC1NR1H4 | |
| SCHEMBL745530 | 0.89 | HDAC1 (0.41) | SRCSLC13A5HDAC1LPAR1LPAR5 | |
| SCHEMBL750906 | 0.88 | TP53 (0.39) | SRCSLC13A5HIF1AHDAC1LPAR1 | |
| SCHEMBL747722 | 0.88 | ESRRG (0.41) | SRCSLC13A5HIF1AHDAC1BCHE | |
| SCHEMBL751065 | 0.87 | SRC (0.38) | SRCSLC13A5HIF1AHDAC1HDAC3 | |
| SCHEMBL749993 | 0.87 | LPAR1 (0.39) | SRCSLC13A5HIF1AHDAC1LPAR1 | |
| SCHEMBL747958 | 0.85 | TP53 (0.38) | SRCSLC13A5HIF1ALPAR1LPAR5 | |
| SCHEMBL748563 | 0.85 | MBTPS1 (0.39) | SRCMBTPS1SLC13A5HDAC3LPAR1 | |
| SCHEMBL750133 | 0.85 | SRC (0.36) | SRCSLC13A5HIF1AHDAC1LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |