Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468832 | 0.89 | TDP1 (0.39) | ALDH1A1L3MBTL1HSD17B10NPC1KDM4E | |
| SCHEMBL7468740 | 0.88 | CYP1A2 (0.43) | ALDH1A1L3MBTL1ALOX15HSD17B10NPC1 | |
| SCHEMBL7653004 | 0.81 | NPC1 (0.49) | ALDH1A1NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL7474491 | 0.80 | KDM4E (0.43) | ALDH1A1L3MBTL1ALOX15HSD17B10NPC1 | |
| SCHEMBL7473689 | 0.78 | ALDH1A1 (0.39) | ALDH1A1KDM4ENPSR1MAPT | |
| SCHEMBL7462635 | 0.76 | RORC (0.38) | ALDH1A1L3MBTL1HSD17B10KDM4ERAB9A | |
| SCHEMBL7469575 | 0.74 | ITGB3 (0.61) | — | |
| SCHEMBL7463190 | 0.74 | GCK (0.40) | ALDH1A1RAB9ASMN1; SMN2TSHRMAPT | |
| SCHEMBL7653781 | 0.73 | WDR5 (0.54) | ALDH1A1ALOX15NPC1KDM4ERAB9A | |
| SCHEMBL7054704 | 0.73 | ALDH1A1 (0.45) | ALDH1A1HSD17B10NPC1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |