Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471265 | 0.86 | ACHE (0.31) | POLBBRD4CREBBP | |
| SCHEMBL7464864 | 0.85 | KDM4E (0.34) | BRD4CREBBP | |
| SCHEMBL7472554 | 0.75 | L3MBTL1 (0.32) | — | |
| SCHEMBL5837610 | 0.68 | MAPT (0.33) | HTR2C | |
| SCHEMBL7468914 | 0.66 | ALDH1A1 (0.30) | — | |
| SCHEMBL7476167 | 0.66 | ALDH1A1 (0.30) | — | |
| SCHEMBL7473201 | 0.65 | AKT1 (0.30) | — | |
| SCHEMBL7466109 | 0.61 | — | — | |
| SCHEMBL31313335 | 0.60 | KDM1A (0.38) | PDE4DHTR2C | |
| SCHEMBL5998722 | 0.60 | MAPK1 (0.42) | HTR2CPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214325-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001019831-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2001-03-22 | — | — | WO | disclosed |