Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.30 |
| ▸ | MTOR | P42345 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473472 | 0.86 | GABRA1 (0.35) | — | |
| SCHEMBL7474476 | 0.85 | PDE4D (0.32) | BRD4CREBBP | |
| SCHEMBL7471265 | 0.83 | ACHE (0.31) | SMN1; SMN2BRD4CREBBP | |
| SCHEMBL7472554 | 0.75 | L3MBTL1 (0.32) | — | |
| SCHEMBL7479571 | 0.75 | STING1 (0.30) | — | |
| SCHEMBL7468914 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL7476167 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL23771943 | 0.68 | KDM4E (0.51) | KDM4EHTTSMN1; SMN2PIK3CAMTOR | |
| SCHEMBL29814717 | 0.68 | KDM4E (0.51) | KDM4EHTTSMN1; SMN2PIK3CAMTOR | |
| SCHEMBL7473201 | 0.67 | AKT1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214325-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001019831-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2001-03-22 | — | — | WO | disclosed |