SCHEMBL7472008

SCHEMBL7472008

Oc1ccc2c(c1)CC[CH]2

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 7/20 0.41
DRD4 P21917 3/20 0.41
CA2 P00918 1/20 0.39
CA5A P35218 1/20 0.39
DRD3 P35462 5/20 0.38
DRD1 P21728 4/20 0.38
DRD5 P21918 3/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
PRKCI P41743 1/20 0.38
OPRK1 P41145 1/20 0.37
ESR2 Q92731 2/20 0.37
ESR1 P03372 1/20 0.37
PBRM1 Q86U86 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CYP3A4 P08684 1/20 0.35
HSP90AA1 P07900 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19926123 0.87 MAOA (0.44) DRD2DRD4CA2CA5ADRD3
SCHEMBL28352287 0.85 MAOA (0.43) DRD2DRD4DRD3DRD1DRD5
SCHEMBL7469508 0.82 CA2 (0.43) DRD2DRD4CA2CA5ADRD3
SCHEMBL1476906 0.78 DRD2 (0.38) DRD2DRD4DRD3DRD1DRD5
SCHEMBL2580002 0.77 HTR2C (0.42)
SCHEMBL2242735 0.73 NOTUM (0.33) DRD2CA2DRD3OPRK1
SCHEMBL1599265 0.73 PNMT (0.39)
SCHEMBL6847406 0.73 CASP1 (0.41) MAOBHSD17B10CYP3A4
SCHEMBL22042262 0.71 DRD2 (0.39) DRD2DRD4DRD3DRD1DRD5
SCHEMBL9995737 0.71 MAOA (0.42) DRD2DRD4DRD3DRD1DRD5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
CN-104955332-B The method of preventing and treating arthropod insect 住友化学株式会社 2017-03-29 CN disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
CN-104955332-A Method for controlling arthropod pest SUMITOMO CHEMICAL CO 2015-09-30 CN disclosed
CN-100591657-C Indane acetic acid compound BAYER PHARMACEUTICALS CORP 2010-02-24 CN disclosed
CN-100528850-C Indane acetic acid derivatives, their use as medicaments, intermediates and processes for their preparation BAYER AG (US) 2009-08-19 CN disclosed
CN-1854118-A Indane acetic acid compound BAYER PHARMACEUTICALS CORP (US) 2006-11-01 CN disclosed
CN-1558905-A Indane acetic acid derivatives, their use as medicaments, intermediates and processes for their preparation ������˹ҩƷ��˾ 2004-12-29 CN disclosed
EP-0650476-B1 PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OTSUKA PHARMA CO LTD (JP) 2002-06-26 EP disclosed
US-6136826-A AMINOPIPERIDINE COMPOUNDS SUBSTITUTED WITH ALKANOYL OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2000-10-24 US disclosed
CN-1052224-C Peripheral Vasodilating agent containing N-acylated 4-amino piperidine derivatives as active ingredients OTSUKA PHARMA CO LTD (JP) 2000-05-10 CN disclosed
US-5760058-A Peripheral vasodilating agent containing piperidine derivative as active ingredient OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-06-02 US disclosed
US-5656642-A Peripheral vasodilating agent containing piperidine derivative as active ingredient OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-08-12 US disclosed
WO-1994022826-A1 PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 DRD2 923/4885DRD4 906/4885CA2 1119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.