Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | F7 | P08709 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA4 | P22748 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SLC2A4 | P14672 | 2/20 | 0.35 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.35 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750133 | 0.86 | SRC (0.36) | F2F10F7SRCSLC13A5 | |
| SCHEMBL746712 | 0.86 | F10 (0.54) | F2F10F7CA12CA1 | |
| SCHEMBL749644 | 0.85 | TACR1 (0.39) | SRCSLC13A5SLC6A4 | |
| SCHEMBL748116 | 0.85 | SRC (0.39) | SRCCA12CA1CA2CA4 | |
| SCHEMBL750906 | 0.84 | TP53 (0.39) | SRCCHRM5CHRM1CHRM3SLC2A4 | |
| SCHEMBL745531 | 0.83 | SRC (0.38) | SRCCA12CA1CA2CA4 | |
| SCHEMBL747958 | 0.80 | TP53 (0.38) | SRCCHRM5CHRM1CHRM3SLC2A4 | |
| SCHEMBL745530 | 0.80 | HDAC1 (0.41) | SRCSLC13A5LPAR1LPAR5 | |
| SCHEMBL749993 | 0.78 | LPAR1 (0.39) | SRCCHRM5CHRM1CHRM3SLC13A5 | |
| SCHEMBL748197 | 0.78 | SRC (0.36) | SRCSLC13A5LPAR1LPAR5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |