Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750906 | 0.87 | TP53 (0.39) | SRCLMNAKDM4EGAATP53 | |
| SCHEMBL745468 | 0.86 | F2 (0.38) | LMNAKDM4EALDH1A1GAATP53 | |
| SCHEMBL748116 | 0.86 | SRC (0.39) | SRCLMNAKDM4EGAASLC13A5 | |
| SCHEMBL747958 | 0.84 | TP53 (0.38) | SRCLMNATP53MAPTCHRM5 | |
| SCHEMBL747255 | 0.83 | F2 (0.43) | SRCLMNAKDM4EGAACHRM5 | |
| SCHEMBL749644 | 0.83 | TACR1 (0.39) | SRCSLC13A5 | |
| SCHEMBL745530 | 0.81 | HDAC1 (0.41) | SRCSLC13A5MEN1KMT2A | |
| SCHEMBL749665 | 0.80 | MAPT (0.42) | SRCLMNAALDH1A1GAATP53 | |
| SCHEMBL747722 | 0.80 | ESRRG (0.41) | SRCLMNAALDH1A1TP53MAPT | |
| SCHEMBL749993 | 0.79 | LPAR1 (0.39) | SRCLMNAALDH1A1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |