Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SLC2A4 | P14672 | 2/20 | 0.33 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL749644 | 0.93 | TACR1 (0.39) | SRCSLC13A5PTGDR2TACR1 | |
| SCHEMBL750906 | 0.92 | TP53 (0.39) | SRCSLC13A5PTGDR2LPAR1LPAR5 | |
| SCHEMBL747958 | 0.88 | TP53 (0.38) | SRCSLC13A5LPAR1LPAR5LMNA | |
| SCHEMBL751093 | 0.87 | CETP (0.39) | SRCSLC13A5PTGDR2GAATACR1 | |
| SCHEMBL745531 | 0.86 | SRC (0.38) | SRCSLC13A5KDM4ELMNAGAA | |
| SCHEMBL745530 | 0.86 | HDAC1 (0.41) | SRCSLC13A5PTGDR2LPAR1LPAR5 | |
| SCHEMBL747101 | 0.85 | F2 (0.39) | SRCSLC13A5PSEN1PSEN2APH1B | |
| SCHEMBL749665 | 0.85 | MAPT (0.42) | SRCSLC13A5LMNAGAAHDAC6 | |
| SCHEMBL747722 | 0.85 | ESRRG (0.41) | SRCSLC13A5LMNAHDAC1HDAC6 | |
| SCHEMBL747255 | 0.85 | F2 (0.43) | SRCSLC13A5LPAR1LPAR5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |