Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479201 | 0.87 | NISCH (0.35) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL7475233 | 0.86 | GFER (0.38) | TNKSTNKS2RAB9AKDM4ENPC1 | |
| SCHEMBL27552770 | 0.86 | ALPL (0.36) | ALDH1A1MGAMGAASIMGAM2 | |
| SCHEMBL7471032 | 0.86 | ALPL (0.36) | ALDH1A1MGAMGAASIMGAM2 | |
| SCHEMBL7465381 | 0.86 | MEN1 (0.33) | ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL7474017 | 0.84 | PKN1 (0.32) | ALDH1A1MGAMGAASIMGAM2 | |
| SCHEMBL27480827 | 0.84 | PKN1 (0.32) | ALDH1A1MGAMGAASIMGAM2 | |
| SCHEMBL7478575 | 0.84 | MAPT (0.40) | TNKSPARP1TNKS2ALDH1A1RAB9A | |
| SCHEMBL7473052 | 0.84 | KDM4E (0.40) | TNKSPARP1TNKS2ALDH1A1TP53 | |
| SCHEMBL7473020 | 0.84 | ALDH1A1 (0.36) | ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1153766-C | Nitroketone compound, its preparing process and pharmaceutical composition containing same | ɪά��ʵ���� | 2004-06-16 | — | — | CN | disclosed |
| EP-0967207-B1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-09-11 | — | — | EP | disclosed |
| US-6034250-A | ANTIOXIDANTS | ADIR ET COMPAGNIE (FR) | 2000-03-07 | — | — | US | disclosed |
| EP-0967207-A1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-12-29 | — | — | EP | disclosed |