Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN1 | Q16512 | 2/20 | 0.32 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27480827 | 1.00 | PKN1 (0.32) | PKN1PKN2NPC1KIF11ALDH1A1 | |
| SCHEMBL7465381 | 0.87 | MEN1 (0.33) | NPC1ALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL7479201 | 0.86 | NISCH (0.35) | NPC1ALDH1A1MAPTHTTRAB9A | |
| SCHEMBL7475233 | 0.85 | GFER (0.38) | NPC1KIF11KDM4ERAB9A | |
| SCHEMBL27481618 | 0.85 | RAB9A (0.38) | NPC1KIF11ALDH1A1MAPTKDM4E | |
| SCHEMBL7472593 | 0.85 | RAB9A (0.38) | NPC1KIF11ALDH1A1MAPTKDM4E | |
| SCHEMBL7472583 | 0.84 | TNKS (0.32) | NPC1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL7471032 | 0.84 | ALPL (0.36) | NPC1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL7478575 | 0.82 | MAPT (0.40) | NPC1ALDH1A1MAPTHTTRAB9A | |
| SCHEMBL7473020 | 0.82 | ALDH1A1 (0.36) | NPC1KIF11ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0967207-B1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-09-11 | — | — | EP | disclosed |
| US-6034250-A | ANTIOXIDANTS | ADIR ET COMPAGNIE (FR) | 2000-03-07 | — | — | US | disclosed |
| EP-0967207-A1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-12-29 | — | — | EP | disclosed |