Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TCF4 | P15884 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 10/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479201 | 0.85 | NISCH (0.35) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7472583 | 0.84 | TNKS (0.32) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL7471032 | 0.84 | ALPL (0.36) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL27552770 | 0.84 | ALPL (0.36) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL7465381 | 0.83 | MEN1 (0.33) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL7474017 | 0.82 | PKN1 (0.32) | ALDH1A1HSD17B10MAPTKDM4ENPC1 | |
| SCHEMBL7473052 | 0.82 | KDM4E (0.40) | ALDH1A1NOX1AURKAMAPTKDM4E | |
| SCHEMBL7462399 | 0.82 | ALOX5 (0.32) | — | |
| SCHEMBL7478575 | 0.82 | MAPT (0.40) | ALDH1A1MAPTNPC1GUSBRAB9A | |
| SCHEMBL7475233 | 0.82 | GFER (0.38) | KDM4ENPC1RAB9AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1153766-C | Nitroketone compound, its preparing process and pharmaceutical composition containing same | ɪά��ʵ���� | 2004-06-16 | — | — | CN | disclosed |
| EP-0967207-B1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-09-11 | — | — | EP | disclosed |
| EP-0967207-A1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-12-29 | — | — | EP | disclosed |