Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472583 | 0.87 | TNKS (0.32) | MEN1NPC1ALDH1A1MAPTNFKB1 | |
| SCHEMBL27552770 | 0.87 | ALPL (0.36) | NPBWR1MEN1NPC1ALDH1A1MAPT | |
| SCHEMBL7471032 | 0.87 | ALPL (0.36) | NPBWR1MEN1NPC1ALDH1A1MAPT | |
| SCHEMBL7465381 | 0.87 | MEN1 (0.33) | NISCHNPBWR1MEN1NPC1ALDH1A1 | |
| SCHEMBL27480827 | 0.86 | PKN1 (0.32) | NPC1ALDH1A1MAPTHTTRAB9A | |
| SCHEMBL7474017 | 0.86 | PKN1 (0.32) | NPC1ALDH1A1MAPTHTTRAB9A | |
| SCHEMBL7473052 | 0.85 | KDM4E (0.40) | NPBWR1MEN1NPC1ALDH1A1MAPT | |
| SCHEMBL7473020 | 0.85 | ALDH1A1 (0.36) | NPC1ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7478575 | 0.85 | MAPT (0.40) | NPBWR1MEN1NPC1ALDH1A1MAPT | |
| SCHEMBL7462399 | 0.85 | ALOX5 (0.32) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0967207-B1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-09-11 | — | — | EP | disclosed |
| US-6034250-A | ANTIOXIDANTS | ADIR ET COMPAGNIE (FR) | 2000-03-07 | — | — | US | disclosed |
| EP-0967207-A1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-12-29 | — | — | EP | disclosed |