Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474017 | 0.87 | PKN1 (0.32) | KDM4EALDH1A1CYP1A2MAPTNPC1 | |
| SCHEMBL7479201 | 0.87 | NISCH (0.35) | MEN1KMT2AALDH1A1NISCHMAPT | |
| SCHEMBL27480827 | 0.87 | PKN1 (0.32) | KDM4EALDH1A1CYP1A2MAPTNPC1 | |
| SCHEMBL7472593 | 0.86 | RAB9A (0.38) | KMT2AKDM4EALDH1A1CYP1A2MAPT | |
| SCHEMBL27481618 | 0.86 | RAB9A (0.38) | KMT2AKDM4EALDH1A1CYP1A2MAPT | |
| SCHEMBL7471032 | 0.86 | ALPL (0.36) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL27552770 | 0.86 | ALPL (0.36) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7472583 | 0.86 | TNKS (0.32) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL7472105 | 0.84 | GAA (0.39) | KDM4EALDH1A1NPBWR1MAP4K4CLK2 | |
| SCHEMBL7473052 | 0.83 | KDM4E (0.40) | MEN1KMT2AKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1153766-C | Nitroketone compound, its preparing process and pharmaceutical composition containing same | ɪά��ʵ���� | 2004-06-16 | — | — | CN | claimed |
| EP-0967207-B1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-09-11 | — | — | EP | claimed |
| US-6034250-A | ANTIOXIDANTS | ADIR ET COMPAGNIE (FR) | 2000-03-07 | — | — | US | claimed |
| CN-1245169-A | Nitroketone compound, its preparing process and pharmaceutical composition containing same | ADIR (FR) | 2000-02-23 | — | — | CN | claimed |
| EP-0967207-A1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-12-29 | — | — | EP | claimed |
| CN-1153766-C | Nitroketone compound, its preparing process and pharmaceutical composition containing same | ɪά��ʵ���� | 2004-06-16 | — | — | CN | disclosed |
| EP-0967207-B1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-09-11 | — | — | EP | disclosed |
| US-6034250-A | ANTIOXIDANTS | ADIR ET COMPAGNIE (FR) | 2000-03-07 | — | — | US | disclosed |
| CN-1245169-A | Nitroketone compound, its preparing process and pharmaceutical composition containing same | ADIR (FR) | 2000-02-23 | — | — | CN | disclosed |
| JP-2000026428-A | NEW NITRONE COMPOUND, ITS PRODUCTION AND MEDICAL COMPOSITION CONTAINING THE SAME | ADIR | 2000-01-25 | — | — | JP | disclosed |
| EP-0967207-A1 | Nitrone derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-12-29 | — | — | EP | disclosed |