Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389702 | 0.87 | MGLL (0.47) | SIGMAR1TSHRALDH1A1LMNAMGLL | |
| SCHEMBL7473955 | 0.86 | MGLL (0.53) | SIGMAR1KMT2AMGLLMEN1 | |
| SCHEMBL5530617 | 0.84 | SIGMAR1 (0.45) | SIGMAR1MGLL | |
| SCHEMBL7384950 | 0.83 | FABP6 (0.46) | SIGMAR1ALDH1A1MGLL | |
| SCHEMBL7387996 | 0.82 | SIGMAR1 (0.49) | SIGMAR1MGLL | |
| SCHEMBL7385750 | 0.82 | SIGMAR1 (0.54) | SIGMAR1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL7074800 | 0.81 | ALDH1A1 (0.60) | KMT2ATSHRALDH1A1LMNAMGLL | |
| SCHEMBL7386854 | 0.80 | DGAT1 (0.42) | SIGMAR1LMNA | |
| SCHEMBL7477320 | 0.80 | MGLL (0.47) | SIGMAR1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL7386012 | 0.79 | LMNA (0.44) | SIGMAR1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056743-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999031092-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |