Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474447 | 0.81 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2TSHRTDP1MAPT | |
| SCHEMBL7476695 | 0.79 | HTT (0.48) | ALDH1A1SMN1; SMN2GAAKMT2AMAPT | |
| SCHEMBL8762462 | 0.78 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2GAAHPGDTSHR | |
| SCHEMBL7475387 | 0.71 | MAPT (0.61) | ALDH1A1SMN1; SMN2EGFRERBB2HPGD | |
| SCHEMBL1668445 | 0.69 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2GLATDP1KMT2A | |
| SCHEMBL7465274 | 0.69 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2GAAKMT2AMAPT | |
| SCHEMBL7463456 | 0.68 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2KMT2AMAPTL3MBTL1 | |
| SCHEMBL28907047 | 0.68 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2TSHRTDP1KMT2A | |
| SCHEMBL7465077 | 0.68 | RORC (0.55) | SMN1; SMN2GAATSHRKMT2AMAPT | |
| SCHEMBL268225 | 0.68 | SIRT6 (0.48) | ALDH1A1SMN1; SMN2TSHRTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |