Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.39 |
| ▸ | CCNK | O75909 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475340 | 0.89 | CYP1A2 (0.43) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL7468744 | 0.89 | CYP1A2 (0.43) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL7468836 | 0.89 | EPHX2 (0.41) | KDM4ESMN1; SMN2MAPTKMT2AKAT2B | |
| SCHEMBL7653004 | 0.87 | NPC1 (0.49) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL7474484 | 0.80 | ALDH1A1 (0.44) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL7473696 | 0.80 | OPRK1 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL446373 | 0.78 | DRD2 (0.49) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL7469825 | 0.77 | MEN1 (0.41) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL7462642 | 0.77 | MEN1 (0.41) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL382924 | 0.76 | ALDH1A1 (0.48) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |