Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 14/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469473 | 0.89 | MAPK8 (0.39) | ALDH1A1ROCK2ROCK1CDC42BPBKDM4E | |
| SCHEMBL382601 | 0.87 | OPRK1 (0.41) | OPRK1ALDH1A1KDM4E | |
| SCHEMBL7475340 | 0.83 | CYP1A2 (0.43) | ALDH1A1ROCK2ROCK1CDC42BPBKDM4E | |
| SCHEMBL7468744 | 0.83 | CYP1A2 (0.43) | ALDH1A1ROCK2ROCK1CDC42BPBKDM4E | |
| SCHEMBL7474491 | 0.80 | KDM4E (0.43) | ALDH1A1KDM4E | |
| SCHEMBL7473689 | 0.78 | ALDH1A1 (0.39) | OPRK1ALDH1A1HCRTR1HCRTR2KDM4E | |
| SCHEMBL7468383 | 0.75 | ITGB3 (0.41) | ALDH1A1KDM4E | |
| SCHEMBL7469825 | 0.75 | MEN1 (0.41) | ALDH1A1ROCK2ROCK1CDC42BPBKDM4E | |
| SCHEMBL7462642 | 0.75 | MEN1 (0.41) | ALDH1A1ROCK2ROCK1CDC42BPBKDM4E | |
| SCHEMBL382455 | 0.75 | DRD2 (0.42) | KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |