Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475194 | 0.91 | EGFR (0.66) | EGFRHTTLMNAKDM4EHPGD | |
| SCHEMBL7474668 | 0.86 | HTT (0.63) | EGFRHTTLMNAKDM4EHPGD | |
| SCHEMBL7473897 | 0.85 | EGFR (0.55) | EGFRHTT | |
| SCHEMBL7473179 | 0.85 | MAPK1 (0.58) | EGFRHTTLMNAMAPT | |
| SCHEMBL7472725 | 0.84 | EGFR (0.61) | EGFRHTT | |
| SCHEMBL7465009 | 0.83 | HTT (0.57) | EGFRHTTLMNAMAPTKDM4E | |
| SCHEMBL7461665 | 0.83 | USP10 (0.59) | EGFRHTTLMNA | |
| SCHEMBL7470641 | 0.82 | EGFR (0.50) | EGFRLMNA | |
| SCHEMBL7460925 | 0.82 | EGFR (0.48) | EGFRHTTLMNAMAPTKDM4E | |
| SCHEMBL7470418 | 0.82 | MAPK1 (0.65) | EGFRHTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |