Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477416 | 0.86 | S1PR1 (0.47) | CASP3CASP7CYP2D6CYP3A4SPHK1 | |
| SCHEMBL7484236 | 0.82 | NPC1 (0.44) | CASP3CASP7CYP2D6ALOX15L3MBTL1 | |
| SCHEMBL7479965 | 0.81 | POLB (0.38) | CASP3CASP7CYP2D6CA12CA2 | |
| SCHEMBL7485723 | 0.81 | FKBP1A (0.40) | CASP3CASP7CYP2D6ALOX15KDM4E | |
| SCHEMBL27031271 | 0.81 | HTR6 (0.47) | CASP3CASP7CYP2D6CYP1A2DRD2 | |
| SCHEMBL31719332 | 0.78 | HTR6 (0.48) | CASP3CASP7CYP2D6CYP1A2DRD2 | |
| SCHEMBL995109 | 0.75 | CA12 (0.54) | CYP2D6CYP3A4CA12CA2CA9 | |
| SCHEMBL12611406 | 0.74 | ATM (0.45) | CASP3CASP7CYP2D6CA12CA2 | |
| SCHEMBL27031270 | 0.74 | ALDH1A1 (0.44) | CASP3CASP7CYP2D6 | |
| SCHEMBL7477516 | 0.74 | MAPT (0.45) | KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |